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Background: Two years after the outbreak of the pandemic, several studies look at the consequences for the well-being and mental health of young people. In particular, creativity and resilience are cited in the scientific literature as resources that promote this well-being in adolescents and young adults. Purpose: This mini-literature review was created with the aim of examining how many articles have explored the relationship between creativity and resilience in adolescents and young adults since the onset of the pandemic. Methods: Particular attention was paid to how many of the articles actually related to the consequences of the pandemic, in which country they were published, their target population, and the models, instruments and variables used to analyze them. Results: Only 4 articles emerged from the screening, of which only one was actually related to pandemic consequences. All articles were published in Asian countries with a target group of university students. Three of the articles used mediation models to examine the relationship between resilience as an independent variable and creativity as a dependent variable. All articles used self-assessment instruments for creativity and resilience, both at the individual and group level. Significance: This mini-review offers us the opportunity to reflect on the lack of studies that have addressed the issue of youth resources in the form of creativity and resilience since the beginning of the pandemic. The results show us a still underdeveloped interest in creativity in the scientific literature, in contrast to what the media reports on the promotion of creativity in daily life.
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Mental Health , Pandemics , Humans , Adolescent , Young Adult , Disease Outbreaks , AsiaABSTRACT
Genellikle insanlar doğumdan itibaren toplumsal cinsiyet rollerine maruz kalarak ilerleyen yaşantılarında bu roller doğrultusunda tüketim tercihlerini ve kararlarını belirlemeye çalışmaktadır. Toplumdan topluma değişen skonusu bu roller, kişilerin vereceği tüketim kararlarında etkili bir pozisyonda yer almasını sağlayabilir. Ancak daha önce yapılmış çalışmalar, küresel bir şokun tüketimler üzerinde bireylerin benzer tüketim tercihlerinde bulunulduğunu göstermiştir. Bu bağlamda çalışmanın amacı Covid-19 salgını ile birlikte toplumun cinsiyetlere yüklediği rollere ait tüketim kalıplarının genç yetişkinler üzerindeki değişiminin ne şekilde yaşandığını ortaya koymayı amaçlamaktadır. Araştırma yöntemi olarak nitel araştırma tekniklerinden derinlemesine mülakat tekniği kullanılmıştır. Çalışma kapsamında Muğla Sıtkı Koçman Üniversitesi Íktisadi ve Ídari Bilimler Fakültesi bünyesinde yer alan bölümlerdeki (işletme, iktisat, kamu yönetimi, siyaset bilimleri ve uluslararası ilişkiler) 40 öğrenci ile bu görüşmeler gerçekleştirilmiştir. Sonuç olarak küresel salgınla birlikte toplumsal cinsiyet algısına aykırı satın alımlar gerçekleştiren katılımcıların son derece az oluşu hatta genç yetişkinlerin büyük çoğunluğunun toplumsal cinsiyete bağlı tüketim yapmadıkları ve buna karşı oldukları ortaya çıkmıştır.Alternate :People are often exposed to gender roles from birth to determine consumption preferences and decisions in line with these roles in their future lives. These roles, which have changed from society to society, can enable people to take an effective position in the decisions of consumption. However, previous studies have shown that individuals have similar consumption preferences on the consumption of a global shock.In this context, the aim of the study is to demonstrate the way that the consumption patterns of the roles that society has put into the gender, along with the Covid-19 epidemic, have changed on young adults. In-depth interview technique from qualitative research techniques was used as a method of research. These meetings were held with 40 students in the departments of the Faculty of Economics and Administrative Sciences (business, economics, public administration, political sciences and international relations) of Muğla Sitki Kocman University within the scope of the study. As a result, participants who have made procurement against the perception of gender with the global outbreak have been extremely low, and even the majority of young adults have shown that they do not consume and oppose gender-dependent consumption.
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Social determinants of mental and physical health that influence young peoples' trajectories into adulthood are often remediable through law. To address inequalities, including those exacerbated since the COVID-19 pandemic, there is a need to better understand young people's need for and uptake of advice for social welfare legal problems. This scoping review aimed to review available evidence and identify gaps to inform further research. To identify studies relevant to social welfare legal advice among young adults we conducted searches of eight bibliographic databases (compiled between January 1998 and June 2020), hand searches of included article reference lists and targeted grey literature searches. 35 peer reviewed and grey literature studies were selected based on inclusion and exclusion criteria including evaluations of interventions to promote access to advice, general population surveys, observational studies, and audits of charity data or targeted surveys. Evidence suggests considerable and inequitable need for social welfare legal advice among young adults with adverse consequences for health and wellbeing. Needs among higher risk groups are likely underestimated. Evidence for interventions to enhance access/uptake of advice is limited and methodologically weak. We identify several gaps in the literature to inform research and to enable systematic reviews around more specific questions to inform practice.
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Until recent decades, labour-intensive subsistence farming was a way of life and livelihood in the hill communities of Uttarakhand, India. However, the nature of agriculture falls far short of the expectations of the main labour force, the rural youth, leading to their mass migration to non-agricultural occupations. The large-scale youth migration has left many hill farming landscapes depopulated and farmlands abandoned. As youth have special stakes in food systems, they must be included in the sustainable transformation of food systems. By doing so, the migration-prone hill region may be transformed into a place where rural youth have more options for work and income. Therefore, the agriculture sector needs to change and develop into a more engaging and youthful workplace. There are opportunities to explore and barriers to be removed. Besides identifying priority research areas on local food systems, in this exploratory research, we investigate opportunities to involve rural young people in the transformation of the food system. We document information by conducting focus group discussion (FGD) meetings in about 100 villages in the Uttarakhand hills, representing all major farming landscapes. This study mainly focuses on improving the production and consumption aspects of local food, which not only benefits the health and wellbeing of local communities but also has many positive economic, social, and environmental effects. In addition, we explore opportunities for reviving mountain agriculture through agri-ecotourism, which is a symbiotic relationship between tourism and agriculture. Making home- or farm stays in agri-ecotourism a subsistence strategy for local youth will contribute to a more prosperous rural economy. Recognising Uttarakhand's rich culture and heritage while exploring the culinary travel opportunities in homestays will provide opportunities to focus more on traditional food systems, exposing various tangible and intangible aspects of the host region's food culture to tourists. The findings of this study will aid in identifying specific policy issues for consideration by planners and policymakers at the local and state levels. Additionally, this exploratory study will assist young, motivated researchers in conducting follow-up, in-depth investigations and producing empirical data in their specialised fields.
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The impact of the COVID-19 pandemic on mental health in young age groups (chil-dren, adolescents, and young adults) has a higher prevalence than individuals at other stages of the lifecycle. The implementation of mental health services faces more barriers to professional care than in the pre-pandemic period. This study aims to identify the effect of sociodemographic and Public Health and Sosial Measures on the mental health of young age groups and mental health services during the COV-ID-19 pandemic. We conducted a mixed-methods-integrated approach to synthesize the findings and drew results using mixed-methods analysis. Literature finding was conducted in seven databases. The selection procedure followed the f low diagram of the Preferred Reporting Items for Systematic Review and Meta-Analyses. Inclusion criteria included all types of research that looked at the impact of COVID-19 on mental health and mental health services. There are 44 articles included, and the quality assessment shows that the study was evaluated as 80% and 100% quality criteria met. During the implementation of Public Health and Social Measures, the young age group experienced mental health problems, including stress, depression, anxiety, sleeping disorder, eating disorder, and post-traumatic stress disorder related to socioeconomic status, academic, and social factors. This systematic review proves that the COVID-19 pandemic affects the mental health of the young age group and mental health services. © 2022, Universitas Negeri Semarang. All rights reserved.
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The "Report on the Condition of Education" is a congressionally mandated annual report from the National Center for Education Statistics (NCES). Using the most recent data available (at the time this report was written) from NCES and other sources, the report contains key indicators on the condition of education in the United States at all levels, from prekindergarten through postsecondary, as well as labor force outcomes and international comparisons. There are core indicators that are updated every year and spotlight indicators that provide in-depth analyses on topics of interest to education agencies, policymakers, researchers, and the public. At the broadest level, the Condition of Education Indicator System is organized into five sections: family characteristics;preprimary, elementary, and secondary education;postsecondary education;population characteristics and economic outcomes;and international comparisons. The Report on the "Condition of Education 2023" encompasses key findings from the Condition of Education Indicator System. The full contents of the Indicator System can be accessed online through the website or by downloading PDFs for the individual indicators. [For "The Condition of Education 2023": At a Glance, see ED628291. For the "Report on the Condition of Education 2022. NCES 2022-144," see ED619870.]
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Early on, whispers of a potentially engineered virus grew and fueled speculation that China was behind the pandemic-speculation so pervasive that, in February 2020, a group of 27 public health scientists published a letter in The Lancet disputing the laboratory leak theory, and announcing their support of their counterparts in China-the scientists, public health officials, and medical professionals-combating the pandemic. Robert Malone, MD, the inventor of the mRNA technology, has expressed strong concern over the risk-benefit analysis of vaccinating young adults, and the Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices has met to discuss cases of myocarditis or pericarditis in people aged 30 and younger who have received an mRNA Covid-19 vaccine. What we do know for certain is that the incredible strength and collaboration of the scientific community have allowed us to regain some semblance of normalcy.
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Robert Malone, an mRNA researcher, appeared on television recently, expressing strong concern over the risk-benefit analysis of vaccination for young adults (3), and the Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices recently met to discuss instances of myocarditis or pericarditis in people aged 30 and younger who have received an mRNA COVID-19 vaccine. What we do know for certain is that the incredible strength and collaboration of the scientific community have allowed us to regain some semblance of normalcy. The development and rollout of multiple effective vaccine options have been the medical miracle of our lifetime.
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BackgroundEducation and employment established in young adulthood predict future lifetime socioeconomic achievements. Young adults with Systemic Lupus Erythematosus (SLE) have physical, cognitive and mental health issues and other comorbidities that may impact employment.ObjectivesTo understand the lived experiences of young adults with SLE (YASLE), as students, and to assess their perceived barriers from SLE.MethodsYASLE were recruited from two Lupus clinics in Toronto and Winnipeg. Semi-structured qualitative interviews were conducted individually via secure video conferencing. As this study was conducted during the coronavirus pandemic, participants were also asked about the pandemic impacts on their education experiences. All interviews were transcribed verbatim, double-coded and analysed using a reflexive thematic approach.ResultsTwelve participants (2 males), 9 of childhood- and 3 adult-onset SLE (cSLE, aSLE) were interviewed. Nine participants (82%) were <25 years old. Five also worked while studying. Five were Asians, 5 were White, 2 of other ethnicities. Half have severe disease (central nervous system or renal involvement). Median duration of disease was 4.0 (25th-75th percentile, 1.8- 5.3) years. The impacts of SLE on their education experience emerged in 5 themes:1) Challenges imposed by SLE: Difficulties adjusting to the diagnosis, physical and cognitive symptoms of SLE. While most participants disclosed their diagnosis to their schools, some expressed hesitation.2) Changes in aspirations: Education/career goals were modified by reducing course load or shifting to more sedentary or less cognitively demanding careers.3) Coping and acceptance: More adaptive than maladaptive coping strategies were used to manage their SLE, including self-acceptance, pacing, planning and avoidance. All strived to do well in their studies despite SLE and were hopeful for their futures.4) Facilitating factors for education success: Family and friends' social support, individualized accommodations from school and parental financial support were identified.5) Pandemic impacts: Virtual learning and flexible schedules enabled participants to adapt their schedules according to their physical conditions (e.g. pain, fatigue). However, fewer opportunities to interact in-person were viewed as challenges. Participants want hybrid options to continue even after the pandemic.ConclusionSLE affected students' performance through physical symptoms, fatigue and cognitive dysfunction. Ongoing social and school supports help to support them. Maintaining the remote learning options may increase accessibility for them. These results identified opportunities for developing future supportive interventions for YASLE patients in their schooling which then better prepare them for future employment.References[1]Jetha A, Badley E, Beaton D, Fortin PR, Shiff NJ, Gignac MA. Unpacking early work experiences of young adults with rheumatic disease: an examination of absenteeism, job disruptions, and productivity loss. Arthritis care & research. 2015;67:1246-54.[2]E. F Lawson, A. O. Hersh, L. Trupin, E. von Scheven, M. J. Okumura, J. Yazdany, et al. Educational and vocational outcomes of adults with childhood and adult onset systemic lupus erythematosus: nine years of follow-up. Arthritis Care Res 2014;66: 717-24.Acknowledgements:NIL.Disclosure of InterestsMike Golding: None declared, Fareha Nishat: None declared, Kaitlyn Merrill: None declared, Ramandeep Kaur: None declared, Jennifer Stinson: None declared, Jennifer Protudjer Speakers bureau: Nutricia (Food allergy university, Nov 2022), Consultant of: Novartis 2021, allergy products, Roberta Woodgate: None declared, Christine Peschken: None declared, Diane Lacaille: None declared, Umut Oguzoglo: None declared, Zahi Touma: None declared, Lily Lim Speakers bureau: Pfizer Feb 2023. Not drug related and not related to this .
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BackgroundCOVID-19 vaccination campaigns successfully impacted on viral spreading and in particular on clinical course of the disease. However, secondary to a highly extended vaccination program, several local and systemic adverse events associated with mRNA COVID-19 vaccines have been reported. Pericarditis and myocarditis are examples of cardiac complications related to these vaccines. In particular, cases of pericarditis have occurred after mRNA COVID-19 vaccination (mostly secondary to vaccination with Moderna than Pfizer-BioNTech), especially in male adolescents and young adults, more often after the second dose. The incidence is approximately of 1-2 cases/100.000.ObjectivesAim of our study was to study the clinical profile of pericarditis occurred within 30 days after COVID-19 vaccines in our clinic.MethodsWe present a case series of patients who developed pericarditis after COVID-19 vaccination in the Department of Internal Medicine at Fatebenefratelli Hospital in Milan, followed from December 1, 2021 to April 15, 2022.ResultsTwenty-five individuals, of which 18 (72%) were women and 7 (28%) were males, had vaccine related pericarditis. Two patients were vaccinated with AstraZeneca, 2 with Moderna, the remaining with Pfizer-BioNTech. Median age was of 42 years. Of all patients, one subject was affected by constrictive effusive pericarditis, while another required treatment of pericarditis with Anakinra, switched to Canakinumab after severe skin reactions, because of failure of therapeutic response to first-line treatments.Two patients required hospital admission, in one case for a transient constrictive pericarditis. In the remaining cases clinical symptoms associated with post-vaccines pericarditis were mild and didn't require hospitalization.Chest pain was reported in 100% of cases, whereas pericardial effusion (in one case larger than 10 mm) was evidenced in 30% of subjects. Eighty percent of patients experienced tachycardia, whereas 90% reported asthenia.An increase in indices of inflammation (CRP) was documented in 50% of patients, usually mild.With regard to therapy, 90% of patients were treated with NSAIDs, 95% with colchicine, while 50% of cases required treatment with low-dose steroids.ConclusionCOVID-19 vaccination induces a particular form of pericarditis, often insidious and very troublesome, but with good prognosis. The clinical phenotype showed less typical chest pain, often normal indices of inflammation and little or no instrumental changes, but patients often experimented tachycardia and functional limitation. With regard to therapy, we used NSAIDs at adequate dosages to control the clinical condition, or low-dose colchicine. Low doses of cortisone (e.g., prednisone 5-10 mg a day) were useful in the presence of marked asthenia or systemic symptoms. Beta-blockers or ivabradine were used in the presence of tachycardia.References[1]Barda N, Children 2021, 8(7), 607;Safety of the BNT162b2 mRNA Covid-19 in a Nationwide setting. N Engl J med 2021;385:1078-1090.[2]Diaz GA, Myocarditis and Pericarditis After Vaccination for COVID-19. JAMA 2021;326 (12): 1210-1212.[3]Bibhuti D, Myocarditis and Pericarditis Following mRNA COVID-19 Vaccination: What Do We Know So Far?. Children 2021, 8(7), 607.[4]Giacomo Maria Viani, Patrizia Pedrotti, Romano Seregni, and Brucato Antonio;Effusive–constrictive pericarditis after the second dose of BNT162b2 vaccine (Comirnaty): a case report;European Heart Journal - Case Reports (2022) 6(2), 1–6.[5]Francesco Perna, Elena Verecchia, Gaetano Pinnacchio, Laura Gerardino, Antonio Brucato, and Raffaele Manna;Rapid resolution of severe pericardial effusion using anakinra in a patient with COVID-19 vaccine-related acute pericarditis relapse:a case report;European Heart Journal - Case Reports (2022) 6, 1–6.Acknowledgements:NIL.Disclosure of InterestsNone Declared.
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The contemporary European context foreshadows many challenges for young people who want to pursue a teaching career. Our study is of interest in the initial preparation for the teaching career of students who have experienced online school and who are required to reconfigure their training in the direction of solid skills, especially digital. Opinion polls reveal a demotivation of students towards school learning, a fact amplified by the Coronavirus pandemic that fundamentally changed the development of the educational process. University departments that train teachers have struggled to provide high-quality training due to the limitations of the pandemic. In the perspective of similar challenges, the initial training of teachers is much more intensely calibrated to the technological needs of education. Requests to increase the quality of education that depend on the quality of teachers are imperative. This study is conducted to find out the opinion of future teachers about the training requirements for the teaching profession. The aim of the study is to survey among young people preparing for teaching careers their motivation for learning in the context and in the perspective of professional teaching standards. The methodology includes recruitment, sampling and application of tools. We used opinion questionnaires to identify the reasons for choosing the initial training in the educational field and the awareness of the difficulties and standards required by this profession. The conclusions of the article indicate that the reasons for choosing a teaching career are diverse, associated with individual options and a superficial knowledge of a teacher's skills. [ FROM AUTHOR] Copyright of Romanian Journal for Multidimensional Education / Revista Romaneasca pentru Educatie Multidimensionala is the property of Lumen Publishing House and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)
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Researchers agree that the predominant scripts of campus sexual culture, normalizing casual encounters with ambiguous distinctions between hookups and dating, offer contradictory risks and rewards for young adults, particularly young women. The arrival of the novel coronavirus in 2020, however, upended the lives of young adults just as they were shaping sexual and romantic careers. We ask, extending critical intersectional approaches, whether the global pandemic, like a natural experiment, might challenge troubling exclusionary as well as gendered aspects of contemporary sexual culture. In‐depth interviews with 40 "twenty‐somethings” completing undergraduate degrees at a selective university at two points over a year apart found that for most the pandemic offered a needed respite. We suggest: first, many young women used the disruption to prioritize their autonomy, with increased partner churn and detachment. Second, some sexual and racial minority participants, and the few with physical disabilities, reported the pandemic normalized their experience as outsiders, strengthening their self‐development. Finally, the more intentional dating practices one participant named "Covid consent” lessened gendered risks of sexual violence and modeled mutual respect for boundaries. While those without class privilege had less ability to enact such boundaries, pandemic challenges may point to healthier, more inclusive sexual scripts. [ FROM AUTHOR] Copyright of Sociological Forum is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)
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The world is facing a serious viral infection caused by the new Severe Acute Respiratory Syndrome Coronavirus 2. We aimed to evaluate and map the high-risk clusters of COVID-19 in the State of Alagoas, a touristic area in northeastern Brazil, after two years of pandemic by a population-based ecological study, using COVID-19 cases reported in the State of Alagoas, between March, 2020 and April, 2022. We performed a descriptive and statistical analysis of epidemiological data. We then map high-risk areas for COVID-19, using spatial analysis, considering the incidence rate by municipality. 297,972 positive cases were registered;56.9% were female and 42.7% aged between 20 and 39 years old. Men (OR = 1.59) and older than 60 years old (OR = 29.64) had a higher risk of death, while the highest incidence rates of the disease occurred in the metropolitan region. Our data demonstrate the impact of COVID-19 in the State of Alagoas, through the two years of pandemic. Although the number of cases were greater among women and young adults, the chance of death was greater among men and older adults. High-risk clusters of the disease initially occur in metropolitan cities and tourist areas.
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Background: The COVID-19 pandemic has sparked anxiety and worry in society. Active cases have continued to grow since the government announced the first patient of COVID-19 in Indonesia. In the midst of this spread, adolescents are one of the dominant groups in society infected with COVID-19. This condition can trigger worry and fear of being infected again. Coupled with the transition of activities that were originally carried out outside the home, they had to change from home only. This situation can affect the psychological condition of adolescents. This study aims to analyze the relationship between the history of COVID-19 and anxiety and symptoms of Obsessive Compulsive Disorder (OCD) in adolescents aged 20-24 years in Surabaya. Subjects and Method: A cross-sectional study was conducted in Surabaya City from October to November 2022. As many as 100 youth aged 20-24 years in Surabaya were the subjects of this study. The dependent variable is anxiety and obsessive compulsive disorder (OCD) symptoms. The independent variable is adolescents aged 20-24 years with a history of COVID-19. The instruments used were questionnaires and PCR swab evidence collection. Research data were analyzed using Pearson's correlation. Results: The results showed that 74 subjects (74%) had mild anxiety. Meanwhile, there were 16 subjects (16%) who had symptoms of OCD. Analysis of the chi-square correlation test between history of COVID-19 disease and anxiety showed that there was no relationship between the two variables with a p value = 0.704. Analysis of the chi-square correlation test between history of COVID-19 disease and OCD symptoms showed that there was no relationship between the two variables with a p value = 0.086. Conclusion: There is no relationship between history of COVID-19 disease and anxiety in adolescents aged 20-24 years in Surabaya and there is no relationship between history of COVID-19 disease and symptoms of Obsessive Compulsive Disorder in adolescents aged 20-24 years in Surabaya.
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B Medium-term cardiac outcomes in young people with multi-system inflammatory syndrome: the era of COVID-19 b I Wong J, Theocharis P, Regan W et al i I Pediatr Cardiol (2022) 43:1728-1736 i Multisystem inflammatory syndrome in children (MIS-C) is a complication of coronavirus disease 2019 (COVID-19). B European Pediatric [sic] Surgeons' Association survey on the use of splenic embolization in blunt splenic trauma in children b I Dariel A i I , i I Soyer T i I , i I Dingemann J et al i I Eur J Pediatr Surg (2022) 32:497-503 i The management of severe splenic injury in children has evolved, and currently the preferred management of even severe injury is nonoperative, with close observation. One of the complications of this and other open-heart procedures requiring cardiopulmonary bypass is acute kidney injury (AKI). [Extracted from the article] Copyright of Pediatric Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)
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Sexual minority young persons may be at risk for compounding mental health effects of the COVID-19 pandemic due to their existing vulnerabilities for psychological inequities. Indeed, recent research has documented that sexual minority young persons are experiencing compounding psychiatric effects associated with the COVID-19 pandemic. Further, researchers and practitioners hypothesized that sexual minority youth and young adults may experience unique hardships related to their sexual and gender identities and familial conflict as a result of the COVID-19 pandemic and living arrangement changes with their parents and families. This study aims to investigate whether there are changes in sexual minority (and non-sexual minority) young adults' (SMYAs) mental health and wellbeing among those living with and living without their parents before and after the start of COVID-19. Among a cross-sectional sample of SMYAs (n=294; Mage=22 years; age range=18-26) and non-SMYAs (n=874; Mage=22 years; age range=18-26) defined by whether they were living with or living without their parents before and after the start of COVID-19, we retrospectively analyzed changes in psychological distress and wellbeing. SMYAs who returned to their parents' homes during post-onset of COVID-19 reported greater mental distress and lower wellbeing, followed by those who were living with their parents both before and after the start of COVID-19. Patterns were not consistent among non-SMYAs, and lower magnitudes of change were seen. There is a significant public health need for mental health services and family education resources for supporting SMYAs in the context of COVID-19 and beyond.
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The main objective of this study was to investigate the dynamic of SARS-CoV-2 viral excretion in rectal swab (RS), saliva, and nasopharyngeal swab (NS) samples from symptomatic patients and asymptomatic contacts. In addition, in order to evaluate the replication potential of SARS-CoV-2 in the gastrointestinal (GI) tract and the excretion of infectious SARS-CoV-2 from feces, we investigated the presence of subgenomic nucleoprotein gene (N) mRNA (sgN) in RS samples and cytopathic effects in Vero cell culture. A prospective cohort study was performed to collect samples from symptomatic patients and contacts in Rio de Janeiro, Brazil, from May to October 2020. One hundred and seventy-six patients had samples collected at home visits and/or during the follow up, resulting in a total of 1633 RS, saliva, or NS samples. SARS-CoV-2 RNA was detected in 130 (73.9%) patients who had at least one sample that tested positive for SARS-CoV-2. The presence of replicating SARS-CoV-2 in RS samples, measured by the detection of sgN mRNA, was successfully achieved in 19.4% (6/31) of samples, whilst infectious SARS-CoV-2, measured by the generation of cytopathic effects in cell culture, was identified in only one RS sample. Although rare, our results demonstrated the replication capacity of SARS-CoV-2 in the GI tract, and infectious viruses in one RS sample. There is still a gap in the knowledge regarding SARS-CoV-2 fecal-oral transmission. Additional studies are warranted to investigate fecal or wastewater exposure as a risk factor for transmission in human populations.
Subject(s)
COVID-19 , Communicable Diseases , Humans , COVID-19/diagnosis , COVID-19/epidemiology , SARS-CoV-2/genetics , RNA, Viral/genetics , Brazil/epidemiology , Prospective StudiesABSTRACT
BACKGROUNDS: The Covid-19 pandemic offered a unique opportunity to investigate trends in hospitalizations related to psychoactive substance intoxication, since the usual health burden of social use at parties and gatherings was likely to be decreased during lockdowns and curfew periods. Since young adults are the main users of psychoactive substances for experimental and recreational purposes, this study identified and compared hospitalization trends in young adults and adults over 30 years old. METHODS: This national cohort study was conducted using the French hospital discharge database. An interrupted time-series analysis for the period between 2014 and 2020 was performed in two groups: young (age 18-29) and other adults (30+) to ascertain the trends in the monthly incidence of hospitalization related to psychoactive substance intoxication (opiates, cocaine, benzodiazepines, psychostimulants, alcohol and cannabis). Hospitalization characteristics during the first and second lockdown and the period between them were compared to the reference period (from 01/01/2014 to 29/02/2020). RESULTS: Among 1,358,007 stays associated with psychoactive substance intoxication, 215,430 concerned young adults. Compared with adults 30+, hospitalization trends in young adults showed a greater decrease in the number of stays during lockdown, with a maximum decrease of -39% during the first lockdown (1,566 vs. 2,576; CI95%: 2,285-2,868) versus -20% (10,212 vs. 12,894; CI95%: 12,001-13,787) in the second lockdown. Presentations for alcohol intoxication decreased throughout the pandemic, particularly during the second lockdown, while admissions for benzodiazepine intoxication increased during both lockdowns. Admissions for cannabis intoxication increased throughout the entire period. CONCLUSIONS: Lockdowns were associated with fewer hospitalizations related to psychoactive substance intoxication in both age groups, especially among young adults, which might reflect a decrease in social use. Recreational use might therefore be an important target for prevention and risk minimization.
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High rates of COVID-19 infection and lower vaccination rates among young adults aged 18 to 26 in the United States prompted this study to examine motivating factors and barriers to COVID-19 vaccination and identify preferences in COVID-19 vaccine education. Three focus group discussions were completed. Transcribed data were analyzed using thematic analysis. Three key themes were identified including (1) motivating factors to vaccination, (2) barriers to vaccination, and (3) COVID-19 vaccination educational intervention design recommendations. Motivating factors included five relevant subthemes: civic duty, fear related to the disease process; fear related to emerging variants and breakthroughs; fear regarding the suffering of others; and freedom. Barriers included four subthemes: lack of trust, misinformation, politics, and pressure. Attempts to further educate young adults about the COVID-19 vaccine should consider strategies that target motivating factors and barriers while also making accurate information accessible through social media.